Synergistic Antifungal Activity of Magnoliae Cortex and Syzyii Flos against Candida albicans

Candida albicans is a dermal fungus of the human body that known to cause oral candidiasis, vaginal and bloodstream infections in immunocompromised people or certain environmental conditions. As cases strains resistant antifungal agents C. have been reported, studies using plant materials as safe are being actively conducted. In this study, total 17 edible extracts showed activity against result evaluating 280-plant extract library paper disk diffusion method. Among them, four with strongest (Cinnamomi Cortex, Cinnamomi Ramulus, Magnoliae Syzygii Flos) were selected evaluated for synergistic albicans. The combination Cortex Flos activity. was based on concentrations magnolol eugenol, respective components Flos. Magnolol eugenol activities at concentration ratio 1:25 – 1:61. these two compounds contributes 28 48% extract. we propose can effectively inhibit growth responsible inhibitory compounds.